- Each capsule contains magnesium salts with the highest bioavailability and absorption (Magnesium Bisglycinate and Magnesium Citrate).
- The herbal capsule dissolves in the intestine. This ensures that the user of Farmafen Mg. Life does not experience the pain in the stomach resulting from the magnesium.
Magnesium is the fourth most common mineral in the human body after calcium, sodium, and potassium. Magnesium acts as a cofactor for 300 enzyme systems, and it is an essential mineral for vital processes such as nucleic acid synthesis. Mg deficiency is very common, and it is encountered as the underlying cause of many everyday physical and mental health problems.
According to the studies conducted in the USA, magnesium deficiency has been reported between 56% and 68%. Possible causes of magnesium deficiency are as follows:
- Many processed products and some inorganic foods have reduced Mg levels.
- Common staple foods such as meat (18-29 mg/100 gm), sugar (0 mg/100 gm) and white flour (20-25 mg) meet less than 20% of the daily Mg requirements.
- Cooking and boiling of the product results in a reduction of the Mg Ingredients.
- Vitamin D deficiency, which is common in Western societies, causes Mg deficiency.
- Some popular medications can reduce the absorption of Mg.
- Smoking and alcohol consumption reduces Mg levels.
- Mg absorption decreases down to 30% due to aging.
Clinical Consequences of Magnesium Deficiency
- Magnesium and Asthma (Level of Evidence: B)
Although its mechanism of action is not fully known, Mg deficiency is known to cause severe bronchospasm in some sensitive individuals.
- Magnesium, Vitamin D, Rickets and Osteoporosis (Level of Evidence: B)
Mg levels must be sufficient to ensure that Vitamin D functions effectively and parathyroid hormone functions properly.
- Magnesium and Muscle Cramps (Level of Evidence: A, B)
Mg supplementation is known to be very beneficial for patients with muscle cramps.
- Magnesium and Pregnancy (Level of Evidence: A, B)
Studies have shown that Mg supplementation during pregnancy reduces the risk of preterm birth, and that it has positive effects on the development of the fetus.
- Magnesium and Migraine (Level of Evidence: A)
Mg supplementation is recommended for the treatment of patients with migraine.
- Relationships Between Magnesium and Prevention of Metabolic Syndrome, Diabetes and Diabetic Complications (Level of Evidence: A, B)
Mg supplementation prevents the development of metabolic syndrome and diabetes. It is protective in patients with diabetes in terms of the development of complications.
- Magnesium and Depression (Level of Evidence: B)
Studies have shown that Mg supplementation can accelerate the recovery of depression, and that it may also be used for preventive purposes.
- Magnesium and Sleep (Level of Evidence: B)
Magnesium is a natural NMDA antagonist and a GABA agonist, facilitating sleep with its relaxing effect.
- Magnesium and Smoking Cessation Therapy (Level of Evidence: B)
Nicotinic cholinergic receptors and NMDA receptors contribute together to the management of presynaptic dopamine.
Mg is a potent inhibitor of the NMDA receptor complex. Including Mg in smoking cessation treatment increases the percentage of success.
- Magnesium and Cancer Treatment (Level of Evidence: A, B)
It is recommended to include MG especially during breast cancer and colon cancer treatments.
- Magnesium and the Cardiovascular System (Level of Evidence: A, B)
It has been demonstrated that supplementation with oral Mg (4.5 g/day Mg pidolate is equivalent to 368 mg/day mg ions) improves vascular and endothelial function in elderly patients with diabetes. It has been reported that there is a 77% reduction in sudden cardiac death in patients with the highest quartile intake of Mg. It is recommended for patients with atrial fibrillation.
- Magnesium and Glaucoma (Level of Evidence: B)
Mg plays an important role in reducing the risk of glaucoma by improving ocular blood flow and preventing ganglion cell loss.
- Magnesium and Stress, Physical Performance, Aging and Lifetime (Level of Evidence: B)
Mg prevents sudden cardiac death and undesired vascular contractions by reducing the level of stress. It improves muscle performance in old age, and can prolong life expectancy by shortening the telomeres.
- Magnesium and Neurological Diseases (Level of Evidence: A, B)
Mg deficiency was reported in the etiology of neurological diseases such as Alzheimer’s and Parkinson’s Diseases.
- Magnesium and Skin (Level of Evidence: B)
Mg salts are known to improve skin hydration, dermal permeability, and barrier repair.
Side Effects
The Institute of Medicine (IOM) reports that the Mg supplement limit is tolerable without side effects at the highest dosage of 350 mg/day. Symptoms of gastric irritation can be seen in tablet form.